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ac710-mesylate

ac710-mesylate

Item no.	V2093-5mg
Manufacturer	InvivoChem LLC
CASRN	1351522-05-8
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1351522-05-8
Available
Description	InvivoChem Cat #:V2093CAS #:1351522-05-8 Purity >=98% Description: AC710 mesylate, the mesylate salt of AC710, is a potent, orally bioactive, and selective inhibitor of PDGFR (platelet-derived growth factor receptor) family kinase with Kd values of 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFRalpha and PDGFRbeta, respectively. As a PDGFR inhibitor, AC710 has potential anticancer activity. Results from a mouse tumor xenograft, a collagen-induced arthritis model, and a 7 day rat in vivo tolerability study culminated in the selection of AC710 as a preclinical development candidate. References: ACS Med Chem Lett. 2012 Sep 24; 3(12):997-1002 Related CAS?: 1351522-04-7 (free base); 1351522-05-8 (mesylate)
Molecular Weight (MW)	658.81
Formula	C??H??N?O?S
CAS No.	1351522-05-8 (mesylate);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: < 1 mg/mL
	Ethanol: N/A
Solubility (In vivo)	O=C(C1=NC=C(OC2CC(C)(C)N(CC)C(C)(C)C2)C=C1)NC3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3. CS(=O)(O)=O
Synonyms	AC 710 Mesylate; AC710 Mesylate; AC-710 Mesylate.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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Delivery expected until 9/4/2025

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