FITM

Item no.	V21041-10mg
Manufacturer	InvivoChem LLC
CASRN	932737-65-0
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V21041CAS #:932737-65-0Purity >=98% Description: FITM is a novel, potent and negative allosteric mGlu1 inhibitor (K_i of 2.5 nM. ). References: 1. WuH, et al. Structure of a class C GPCR metabotropic glutamate receptor 1bound to an allosteric modulator. Science. 2014 Apr 4; 344(6179):58-64. 2. BaiQ, et al. Investigation of allosteric modulation mechanism ofmetabotropic glutamate receptor 1 by molecular dynamics simulations, free energy and weak interaction analysis. Sci Rep. 2016 Feb 18; 6:21763. 3. YamasakiT, et al. In vivo measurement of the affinity and density ofmetabotropic glutamate receptor subtype 1 in rat brain using 18F-FITM insmall-animal PET. J Nucl Med. 2012 Oct; 53(10):1601-7.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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