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geniposidic-acid

geniposidic-acid

Item no.	V2363-5mg
Manufacturer	InvivoChem LLC
CASRN	27741-01-1
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	27741-01-1
Available
Description	InvivoChem Cat #:V2363CAS #:27741-01-1Purity >=98% Description: Geniposidic acid is an iridoid glucoside, used to treat inflammation, jaundice and hepatic disorders. Geniposidic acid shows a more remarkable inhibitory activity factor against implanted tumor growth when the doses of 500 mg/kg are given alone or combined with irradiation. Geniposidic acid improves the plaque area, intima/media thickness ratio, and intimal foam cells number in rabbits. Geniposidic acid (100?ug/mL) results in relieving ECs shedding and improving aortic morphology disorders in rabbits. Geniposidic acid (100?ug/mL) performs significant inhibition on smooth muscle cells proliferation in rabbits. Geniposidic acid results in obvious inhibition on SMC migration from the upper chamber. References: Cancer Lett. 1997 Feb 26; 113(1-2):31-7; Pharm Biol. 2015 Feb; 53(2):280-5; J Ethnopharmacol. 2013 Mar 7; 146(1):271-7.
Molecular Weight (MW)	374.34
Formula	C16H22O10
CAS No.	27741-01-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 16 mg/mL (42.7 mM)
	Water: < 1 mg/mL
	Ethanol: 2 mg/mL (5.3 mM)
Other info	InChi Key: ZJDOESGVOWAULF-OGJQONSISA-N InChi Code: InChI=1S/C16H22O10/c17-3-6-1-2-7-8(14(22)23)5-24-15(10(6)7)26-16-13(21)12(20)11(19)9(4-18)25-16/h1, 5, 7, 9-13, 15-21H, 2-4H2, (H, 22, 23)/t7-, 9-, 10-, 11-, 12+, 13-, 15+, 16+/m1/s1 SMILES Code: O=C(C1=CO[CH](O[CH]2O[CH](CO)[CH](O)[CH](O)[CH]2O)[C]3([H])[C]1([H])CC=C3CO)O
Synonyms	(1S, 4aS, 7aS)-7-(hydroxymethyl)-1-(((2S, 3R, 4S, 5S, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1, 4a, 5, 7a-tetrahydrocyclopenta[c]pyran-4-carboxylic acid

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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