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Moxonidine (BDF5895)

Moxonidine (BDF5895)

Item no.	V2386-5mg
Manufacturer	InvivoChem LLC
CASRN	75438-57-2
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	75438-57-2
Available
Description	InvivoChem Cat #:V2386CAS #:75438-57-2 Purity >=98% Description: Moxonidine (also known as BDF5895) is a potent and selective agonist at the imidazoline receptor subtype 1, and is used as centrally active antihypertensive agent. Moxonidine can bind to both I1-imidazoline receptor (I1R) and alpha2-adrenergic receptor (alpha2AR). The selectivity of moxonidine for I1R is 33-fold over alpha2AR. Moxonidine plays its antihypertensive role in the central nervous system. It has a central site of action. It is shown no effect in pithed rats and in cats following spinal cord transaction. Moxonidine also reduces sympathetic outflow and lowers peripheral vascular resistence. References: J Cardiovasc Pharmacol. 2004 Feb; 43(2):306-11; J Hum Hypertens. 1997 Oct; 11(10):629-35; Br J Pharmacol. 1995 Feb; 114(4):751-4. Related CAS #: 75438-58-3 (HCl) 75438-57-2 (free base)
Molecular Weight (MW)	241.68
Formula	C9H12ClN5O
CAS No.	75438-57-2
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 24 mg/mL (99.3 mM)
	Water: < 1 mg/mL
	Ethanol: 2 mg/mL (8.3 mM)
Solubility (In vivo)	Chemical Name: 4-Chloro-5-(2-imidazolin-2-ylamino)-6-methoxy-2-methylpyrimidine InChi Key: WPNJAUFVNXKLIM-UHFFFAOYSA-N InChi Code: InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2, 1-2H3, (H2, 11, 12, 15) SMILES Code: CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1
Synonyms	BDF-5895; BDF5895; BDF 5895; Cynt; Nucynt; BE 5895; BE-5895; BE5895

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Amount: 5 mg

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Delivery expected until 11/6/2025

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