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Licochalcone B

Licochalcone B

Item no.	V24107-10mg
Manufacturer	InvivoChem LLC
CASRN	58749-23-8
Amount	10 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V24107CAS #:58749-23-8Purity >=98% Description: Licochalcone B, a naturally occuring chalcone compound isolated from the root of Glycyrrhiza inflate, is an inhibitor of phosphorylation of NF-kappaB p65 in LPS signaling pathway. It also inhibits amyloid beta (Abeta42) self-aggregation (IC50=2.16 uM) and disaggregate pre-formed Abeta42 fibrils, reduce metal-induced Abeta42 aggregation through chelating metal ions. References: Kang TH, Yoon G, Kang IA, Oh HN, Chae JI, Shim JH. Natural Compound Licochalcone B Induced Extrinsic and Intrinsic Apoptosis in Human Skin Melanoma (A375) and Squamous Cell Carcinoma (A431) Cells. Phytother Res. 2017 Dec; 31(12):1858-1867. doi: 10.1002/ptr.5928. Epub 2017 Oct 13. PubMed PMID: 29027311.

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Amount: 10 mg

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