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Lifitegrast sodium (SAR-1118)

Lifitegrast sodium (SAR-1118)

Item no.	V24129-10mg
Manufacturer	InvivoChem LLC
CASRN	1119276-80-0
Amount	10 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V24129CAS #:1119276-80-0Purity >=98% Description: Lifitegrast sodium (SAR 1118) is a novel and potent integrinlymphocyte function-associated antigen-1 (LFA-1) antagonist with the potential for Treatment of Dry Eye Disease. It inhibitsJurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. References: Lifitegrast, a Novel Integrin Antagonist for Treatmentof Dry Eye Disease. Ocul Surf. 2016 Apr; 14(2):207-15.2. Sun Y, et al. Corneal inflammation is inhibited by the LFA-1antagonist, lifitegrast (SAR 1118). J Ocul Pharmacol Ther. 2013May; 29(4):395-402 Related CAS #: 1119276-80-0 (sodium salt) 1025967-78-5 (free)

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Amount: 10 mg

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