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Reboxetine mesylate (FCE20124; PNU155950E)

Reboxetine mesylate (FCE20124; PNU155950E)

Item no.	V2433-50mg
Manufacturer	InvivoChem LLC
CASRN	98769-84-7
Amount	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2433CAS #:98769-84-7Purity >=98% Description: Reboxetine (also known as PNU 155950E; Trade name: Edronax) is a selective norepinephrine reuptake inhibitor with Ki of 8.2 nM and antidepressant activity. Reboxetine dose-dependently and completely inhibits 3H-dopamine uptake to the human norepinephrine transporters (hNET) with Ki value of 11 nM in Madin–Darby canine kidney (MDCK) cells. Reboxetine dose-dependently and potently inhibits locus coeruleus neuronal firing in rats with ED50 of 191 ug/kg. Reboxetine inhibition of the locus coeruleus neurons is reversible by the alpha2 antagonist piperoxan (1.5 mg/kg, IV). Reboxetine dose-dependently reverses reserpine-induced blepharospasm and hypothermia in the mouse. References: Biol Psychiatry. 2000 May 1; 47(9):818-29; J Clin Psychiatry. 2002 Jan; 63(1):31-7; J Clin Psychiatry. 1999 Jun; 60(6):400-6. Related CAS: 71620-89-8 (free)
Molecular Weight (MW)	409.5
Formula	C19H23NO3.CH4O3S
CAS No.	98769-84-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 82 mg/mL (200.2 mM)
	Water: < 1 mg/mL
	Ethanol: 82 mg/mL (200.2 mM)
SMILES Code	CCOC1=CC=CC=C1OC(C2CNCCO2)C3=CC=CC=C3.CS(=O)(=O)O
Synonyms	PNU 155950E; PNU155950E; PNU-155950E; FCE-20124 mesylate; PNU-155950E mesylate; FCE 20124 mesylate; PNU 155950E mesylate; FCE20124 mesylate; PNU155950E mesylate; Reboxetine mesilate; Reboxetine; Edronax; Reboxetine mesylate; Vestra (TN); AC1L2RIX; AC1Q6WCV; DSSTox_CID_25690; DSSTox_RID_81062; DSSTox_GSID_45690.

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Amount: 50 mg

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Delivery expected until 9/4/2025

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