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PF-06835919

PF-06835919

Item no.	V25154-50mg
Manufacturer	InvivoChem LLC
CASRN	2102501-84-6
Amount	50 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V25154CAS #:2102501-84-6Purity >=98% Description: PF-06835919 is a novel and potent ketohexokinase (KHK) inhibitor with IC50s of 8.4 nM and 66 nM for KHK-C and KHK-A and with the potential for the Treatment of Metabolic Disorders Driven by the Overconsumption of Fructose. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to further elucidate the effect of KHK inhibition on these metabolic disorders. References: 1. US 20170183328 A1 2. https://doi.org/10.1021/acs.jmedchem.0c00944

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 mg

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Delivery expected until 7/3/2025

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