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Description: CD38 inhibitor 78c is a novel and potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38, exhibiting cardiac protection effects in an ex vivo model of i/r.
References: Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es asPotent CD38 Inhibitors. J Med Chem. 2015 Apr 23; 58(8):3548-71.
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