« Back
Home /
temozolomide

temozolomide

Item no.	V2536-1g
Manufacturer	InvivoChem LLC
CASRN	85622-93-1
Amount	1g
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V2536CAS #:85622-93-1Purity >=98% Description: Temozolomide (Methazolastone; CCRG81045; NSC 362856; SCH 52365; MB39831; and RP46161) is an orally bioavailable and brain penetrant DNA alkylating agent / damage inducer used as an anticancer drug. Methazolastone causes formation of DNA alkali-labile sites which are present in similar amounts and repaired at a similar rate in L-1210 and L-1210/BCNU cell lines. In L-1210 but not in L-1210/BCNU methazolastone induces an arrest of cells in SL-G2-M phases. Methazolastone sensitivity of both chemo-sensitive and resistant cells (D54-R and U87-R) is enhanced significantly under hyperoxia. References: Cancer Res. 1987 Sep 15; 47(18):4884-9. Related CAS#: 113942-30-6 (Temozolomide Acid)
Molecular Weight (MW)	194.15
Formula	C6H6N6O2
CAS No.	85622-93-1
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 38 mg/mL (195.7 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	5% DMSO+30% PEG 300+ddH2O: 2 mg/mL
Synonyms	CCRG81045, NSC362856; NSC 362856; CCRG 81045; NSC-362856; CCRG-81045; SCH-52365; SCH52365; SCH 52365; MB39831; MB-39831; MB 39831; RP46161; RP 46161; R-P46161; CCRG81045; TMZ. US trade names: Methazolastone; Temodar. Foreign brand name: Temodal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1g

available

Delivery expected until 7/3/2025

Express Delivery: Save 17 days

Compare

Add to wishlist

Recommend by mail