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psoralen

psoralen

Item no.	V2565-5mg
Manufacturer	InvivoChem LLC
CASRN	66-97-7
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	66-97-7
Available
Description	InvivoChem Cat #:V2565CAS #:66-97-7Purity >=98% Description: Psoralen (psoralene, Ficusin, Furocoumarin) is a naturally occurring furocoumarin isolated from Fructus Psoraleae, it intercalates with DNA, inhibiting DNA synthesis and cell division. Psoralen inhibits the proliferation of MCF-7/ADR cells as shown by G0/G1 phase arrest rather than encouraging apoptosis. Psoralen reverses MDR(multidrug resistance) through inhibiting ATPase activity rather than reducing P-gp expression. Psoralen inhibits the migration abilities of MCF-7/ADR cells by repressing EMT possibly through inhibiting the activation of NF-kappaB. Psoralens are photoactive compounds that readily alkylate DNA when activated by longwave ultraviolet light. Description: References: Biol Pharm Bull. 2016 May 1; 39(5):815-22; Afr Health Sci. 2014 Sep; 14(3):641-7; Fitoterapia. 2013 Dec; 91:205-10. References:
Molecular Weight (MW)	186.16
Formula	C11H6O3
CAS No.	66-97-7
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 37 mg/mL (198.8 mM)
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES	O=C1C=CC2=CC3=C(OC=C3)C=C2O1
Synonyms	psoralene, Ficusin, Furocoumarin

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Amount: 5 mg

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