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Nebivolol HCl (R 065824)

Nebivolol HCl (R 065824)

Item no.	V26343-250mg
Manufacturer	InvivoChem LLC
CASRN	152520-56-4
Amount	250 mg
Quantity options	100 mg 10 mg 1 g 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V26343CAS #:152520-56-4Purity >=98% Description: Nebivolol (also known as R-65824) potently and selectively inhibits beta1-adrenoceptor with IC50 of 0.8 NM. Nebivolol shows high affinity and selectivity for beta 1-adrenergic receptor sites in a rabbit lung membrane preparation (Ki value = 0.9 nM and beta 2/beta 1 ratio = 50). Nebivolol displays beta1-adrenoceptor selectivity with the Ki(beta2)/Ki(beta1) value of 40.7 judged by competition experiments to 3H-CGP 12.1777 in the presence of CGP 207.12 A (300 nM, Kibeta2) or ICI 118.551 (50 nM, Kibeta1). References: Mol Pharmacol. 1988 Dec; 34(6):843-51; Circ J. 2008 Apr; 72(4):660-70.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 250 mg

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