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BOC-D-FMK

BOC-D-FMK

Item no.	V29824-10mg
Manufacturer	InvivoChem LLC
CASRN	634911-80-1
Amount	10 mg
Quantity options	100 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V29824CAS #:634911-80-1Purity >=98% Description: Boc-D-FMK is a cell-permeable, irreversible (covalent) and broad spectrum caspase inhibitor; inhibits apoptosis stimulated by TNF-alpha with an IC50 of 39 uM. References: 1. YeeSB, et al. zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 actingon 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells. Exp MolMed. 2006 Dec 31; 38(6):634-42. 2. Sheen-ChenSM, et al. Effect of Boc-D-Fmk on hepatocyte apoptosis after bile ductligation in rat and survival rate after endotoxin challenge. JGastroenterol Hepatol. 2008 Aug; 23(8 Pt 1):1276-9. 3. ChanYM, et al. Inhibition of caspases promotes long-term survival andreinnervation by axotomized spinal motoneurons of denervated muscle innewborn rats. Exp Neurol. 2003 Jun; 181(2):190-203.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10 mg

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