Comparison

Procaine (Novocaine)

Item no. V29996-100g
Manufacturer InvivoChem LLC
CASRN 59-46-1
Amount 100 g
Quantity options 10 g 1 g 2 g 50 g 5 g
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V29996CAS #:59-46-1Purity >=98%

Description: Procaine (also known as Novocaine HCl), the HCl salt of the local anestheticProcaine, is an inhibitor of sodium channel, NMDA receptor and nAChRwith IC50 of 60 uM, 0.296 mM and 45.5 uM, which is also an inhibitor of5-HT3 with KD of 1.7 uM. Procaine acts mainly by inhibiting sodiuminflux through voltage gated sodium channels in the neuronal cellmembrane of peripheral nerves. Procaine has also been shown to bind orantagonize the function of N-methyl-D-aspartate (NMDA) receptors as wellas nicotinic acetylcholine receptors and the serotonin receptor-ionchannel complex.

References: Anesth Analg. 1998 Oct; 87(4):885-9; Br J Anaesth. 2006 Jan; 96(1):77-87.

Related CAS #:51-06-9 (free base) 51-05-8 (HCl)

Description: Procaine (also known as Novocaine HCl), the HCl salt of the local anestheticProcaine, is an inhibitor of sodium channel, NMDA receptor and nAChRwith IC50 of 60 uM, 0.296 mM and 45.5 uM, which is also an inhibitor of5-HT3 with KD of 1.7 uM. Procaine acts mainly by inhibiting sodiuminflux through voltage gated sodium channels in the neuronal cellmembrane of peripheral nerves. Procaine has also been shown to bind orantagonize the function of N-methyl-D-aspartate (NMDA) receptors as wellas nicotinic acetylcholine receptors and the serotonin receptor-ionchannel complex.

References: Anesth Analg. 1998 Oct; 87(4):885-9; Br J Anaesth. 2006 Jan; 96(1):77-87.

Related CAS #:51-06-9 (free base) 51-05-8 (HCl)

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 g
Available: In stock
available

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