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mexiletine-hydrochloride

mexiletine-hydrochloride

Item no.	V30244-100mg
Manufacturer	InvivoChem LLC
CASRN	1329835-60-0
Amount	100 mg
Quantity options	1 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V30244CAS #:1329835-60-0Purity >=98% Description: Mexiletine D6 hydrochloride (KOE-1173 D6 HCl) is a deuterated form of Mexiletine hydrochloride (KOE-1173 hydrochloride), which belongs to Class IB anti-arrhythmic groupof medicines, and is a non-selective voltage-gated sodium channel blockerthat inhibits sodium channels to reduce the inward sodium current.Mexiletine is a local anesthetic, antiarrhythmic agent (Class Ib), structurally similar to lidocaine, but orally active. Mexiletine, inhibits the inward sodium current required for the initiation andconduction of impulses, thus reducing the rate of rise of the actionpotential. It achieves this reduced sodium current by inhibiting sodiumchannels. References: Curr Med Chem. 2015; 22(11):1400-13; Curr Pain Headache Rep. 2010 Apr; 14(2):145-50. Related CAS #:31828-71-4 (free) 5370-01-4 (HCl) 1329835-60-0 (D6 HCl) Description: Mexiletine D6 hydrochloride (KOE-1173 D6 HCl) is a deuterated form of Mexiletine hydrochloride (KOE-1173 hydrochloride), which belongs to Class IB anti-arrhythmic groupof medicines, and is a non-selective voltage-gated sodium channel blockerthat inhibits sodium channels to reduce the inward sodium current.Mexiletine is a local anesthetic, antiarrhythmic agent (Class Ib), structurally similar to lidocaine, but orally active. Mexiletine, inhibits the inward sodium current required for the initiation andconduction of impulses, thus reducing the rate of rise of the actionpotential. It achieves this reduced sodium current by inhibiting sodiumchannels. References: Curr Med Chem. 2015; 22(11):1400-13; Curr Pain Headache Rep. 2010 Apr; 14(2):145-50. Related CAS #:31828-71-4 (free) 5370-01-4 (HCl) 1329835-60-0 (D6 HCl)

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Amount: 100 mg

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