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Boceprevir (EBP-520; SCH-503034)

Boceprevir (EBP-520; SCH-503034)

Item no.	V3157-5mg
Manufacturer	InvivoChem LLC
CASRN	394730-60-0
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	394730-60-0
Available
Description	InvivoChem Cat #:V3157CAS #:394730-60-0Purity >=98% Description: Boceprevir (previously known as EBP 520; SCH 503034; trade name: Victrelis) is a novel, orally bioavailable, selective, direct acting inhibitor of hepatitis C virus (HCV) protease with Ki value of 14 nM for NS3 in an enzyme assay and EC90 of 350 nM in cell-based replicon assay. It is an FDA approved drug (trade name: Victrelis) used in combination with other antiviral agents for the treatment of chronic hepatitis C, genotype 1. It exerts the effects by binding to the nonstructural 3 NS3 (HCV) active site of HCV. Description: References: Acc Chem Res. 2008 Jan; 41(1):50-9; Antimicrob Agents Chemother. 2012 Nov; 56(11): 5728–5734. References: Related CAS#: 958002-36-3 (HCl)
Molecular Weight (MW)	519.68
Formula	C27H45N5O5
CAS No.	394730-60-0
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 100 mg/mL (192.4 mM)
	Water: < 1 mg/mL
	Ethanol: > 100 mg/mL (192.4 mM)
Other info	Chemical Name: (1R, 2S, 5S)-N-(4-amino-1-cyclobutyl-3, 4-dioxobutan-2-yl)-3-((S)-2-(3-(tert-butyl)ureido)-3, 3-dimethylbutanoyl)-6, 6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide InChi Key: LHHCSNFAOIFYRV-DOVBMPENSA-N InChi Code: InChI=1S/C27H45N5O5/c1-25(2, 3)20(30-24(37)31-26(4, 5)6)23(36)32-13-15-17(27(15, 7)8)18(32)22(35)29-16(19(33)21(28)34)12-14-10-9-11-14/h14-18, 20H, 9-13H2, 1-8H3, (H2, 28, 34)(H, 29, 35)(H2, 30, 31, 37)/t15-, 16?, 17-, 18-, 20+/m0/s1 SMILES Code: O=C([CH]1[C]2([H])C(C)(C)[C]2([H])CN1C([CH](NC(NC(C)(C)C)=O)C(C)(C)C)=O)NC(C(C(N)=O)=O)CC3CCC3
Synonyms	EBP 520; EBP-520; EBP520; SCH-503034; SCH503034; SCH 503034; trade name: Victrelis.
SMILES Code	O=C(N1[CH]([C]2([H])C(C)([C]2(C1)[H])C)C(NC(C(C(N)=O)=O)CC3CCC3)=O)[CH](NC(NC (C)(C)C)=O)C(C)(C)C

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Amount: 5 mg

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Delivery expected until 11/6/2025

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