Comparison

Rosuvastatin D6 Sodium

Item no. V3296-5mg
Manufacturer InvivoChem LLC
CASRN 2070009-41-3
Amount 5 mg
Quantity options 10 mg 25 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1279031-70-7
Available
Description
InvivoChem Cat #:V3296CAS #:N/A (Rosuvastatin D6 Calcium); N/A ( Rosuvastatin D6 Sodium); 1279031-70-7 (Rosuvastatin D3 Sodium); 287714-41-4 (Rosuvastatin); 147098-20-2 (Rosuvastatin calcium)Purity >=98%

Description: Rosuvastatin D6 Sodium is deuterium labeled Rosuvastatin (also known as S-4522 and ZD 4522, trade name: Crestor) which is a member of the statin class of drugs and a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay. Rosuvastatin belongs to the statin class that is used for the treatment of high cholesterol and related conditions such as dyslipidemia, and to prevent cardiovascular disease. Its approximate elimination half life is 19 h and its time to peak plasma concentration is reached in 3–5 h following oral administration. In 2013 Crestor was the fourth-highest selling drug in the United States, accounting for approx. $5.2 billion in sales.

Description:

References: Clin Pharmacol Ther. 2004 May; 75(5):455-63; Bioorg Med Chem. 1997 Feb; 5(2):437-44.

References:


Molecular Weight (MW)
509.56
Formula
C??H??D?FN?NaO?S
CAS No.
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: 10 mM
Water:
Ethanol:
Solubility (In vivo)

Synonyms
Rosuvastatin: (ZD 4522; ZD-4522; ZD4522; S-4522; S 4522; S4522; Brand name: Crestor).
Chemical Name

SMILES Code
O=C([O-])C[CH](O)C[CH](O)/C=C/C1=C(C(C([2H])([2H])[2H])C([2H])([2H])[2H])N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[Na+]

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 5 mg
Available: In stock
available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question

Submit a bulk request

Questions about this Product?
 
Close