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EG00229 TFA

EG00229 TFA

Item no.	V33581-5mg
Manufacturer	InvivoChem LLC
CASRN	1210945-69-9
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1210945-69-9
Available
Description	InvivoChem Cat #:V33581CAS #:1210945-69-9Purity >=98% Description: EG00229 is a novel and potent Neuropilin 1 (NRP1) receptor antagonist that selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 uM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2. EG00229 inhibits VEGFA binding to NRP1. References: 1. Jarvis A, et al. Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction. J Med Chem. 2010 Mar 11; 53(5):2215-26. 2. Grun D, et al. VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors. Oncogene. 2016 Aug 18; 35(33):4379-87. Related CAS #: 1018927-63-3 (free base) 1210945-69-9 (TFA)

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 5 mg

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