« Back
Home /
bms-830216

bms-830216

Item no.	V3469-100mg
Manufacturer	InvivoChem LLC
CASRN	1197420-06-6
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3469CAS #:1197420-06-6 Purity >=98% Description: BMS-830216 is a prodrug of BMS-819881 which is a novel and potent antagonist of MCHR1 (Melanin concentrating hormone receptor 1) with minimal hERG activity. It binds to rat MCHR1 with a Ki of 7 nM and is also selective for CYP3A4 activity with an EC50 of 13 uM. BMS-819881 has the potential to be used as an anti-obesity drug. It is currently under investigation in Phase 1 clinical trial for treating obesity as the phosphate ester pro-drug (BMS-830216). References: J Med Chem. 2014 Sep 25; 57(18):7509-22.
	Name: BMS-830216 CAS#: 1197420-06-6 Chemical Formula: C24H22ClN2O7PS Exact Mass: 548.0574 Molecular Weight: 548.93 Elemental Analysis: C, 52.51; H, 4.04; Cl, 6.46; N, 5.10; O, 20.40; P, 5.64; S, 5.84
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BMS-830216; BMS 830216; BMS830216 Chemical Name: (R)-2-(4-(6-(4-Chlorophenyl)-4-oxothieno[3, 2-d]pyrimidin-3(4H)-yl)-2-methoxyphenoxy)-1-cyclopropylethyl dihydrogen phosphate InChi Key: YDTUJCNTIMWHPJ-NRFANRHFSA-N InChi Code: InChI=1S/C24H22ClN2O7PS/c1-32-20-10-17(8-9-19(20)33-12-21(14-2-3-14)34-35(29, 30)31)27-13-26-18-11-22(36-23(18)24(27)28)15-4-6-16(25)7-5-15/h4-11, 13-14, 21H, 2-3, 12H2, 1H3, (H2, 29, 30, 31)/t21-/m0/s1 SMILES Code: O=P(O)(O[CH](C1CC1)COC2=CC=C(N(C=NC3=C4SC(C5=CC=C(Cl)C=C5)=C3)C4=O)C=C2OC)O

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100mg

available

Delivery expected until 7/31/2025

Express Delivery: Save 1 days

Compare

Add to wishlist

Get an offer