amikacin

InvivoChem Cat #:V3548CAS #:39831-55-5 Purity >=98%

Description: Amikacin is an aminoglycoside antibiotic used for a number of bacterial infections including joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used either by injection into a vein or muscle. Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side effects include paralysis, resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins.

References: Mayo Clin Proc, 1999. 74(5): p. 519-28.

Related CAS#:37517-28-5 (free base, Inquiry); 1257517-67-1 (hydrate, Inquiry)

-20C for 3 years in powder form

Synonym: BAY-416651 sulfate; BAY416651 sulfate; BAY416651 sulfate; Amikacin sulfate; Amitrex; Antibiotic BB-K8 sulfate; BB-K8; Biklin; Biodacyn; Chemacin; Fabianol; Kaminax; Kancin-Gap; Likacin; Lukadin; BB K8; BBK8
Chemical Name: (S)-4-amino-N-((1R, 2S, 3S, 4R, 5S)-5-amino-2-(((2S, 3R, 4S, 5S, 6R)-4-amino-3, 5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4-(((2R, 3R, 4S, 5S, 6R)-6-(aminomethyl)-3, 4, 5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)-2-hydroxybutanamide bis(sulfate)
InChi Key: FXKSEJFHKVNEFI-GCZBSULCSA-N
InChi Code: InChI=1S/C22H43N5O13.2H2O4S/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21; 2*1-5(2, 3)4/h6-19, 21-22, 28-35H, 1-5, 23-26H2, (H, 27, 36); 2*(H2, 1, 2, 3, 4)/t6-, 7+, 8-, 9+, 10+, 11-, 12+, 13+, 14+, 15-, 16+, 17-, 18+, 19-, 21+, 22+; ; /m0../s1
SMILES Code: NCC[CH](C(N[CH]1C[CH]([CH]([CH]([CH]1O[CH]2O[CH]([CH]([CH]([CH]2O)N)O)CO)O)O[CH]3O[CH]([CH]([CH]([CH]3O)O)O)CN)N)=O)O.OS(=O)(O)=O.OS(=O)(O)=O