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atuveciclib-s-enantiomer

atuveciclib-s-enantiomer

Item no.	V3688-25mg
Manufacturer	InvivoChem LLC
CASRN	N/A
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3688CAS #:N/APurity >=98% Description: Atuveciclib S-enantiomer (formerly known as BAY-1143572 S-Enantiomer) is novel, potent, oral and highly selective PTEFb/CDK9 inhibitor. It inhibits CDK9/CycT1 with an IC50 of 16 nM and is more than 100-fold more selective for CDK9 over CDK2. It also inhibits GSK3 kinase with IC50 values of 45 nM and 87 nM for GSK3alpha and GSK3beta respectively. Atuveciclib is currently in Phase I clinical trial. References: ChemMedChem. 2017 Nov 8; 12(21):1776-1793.; Molecules. 2018, 23(5). pii: E1057. Related CAS#:1414943-88-6 (Atuveciclib)
Molecular Weight (MW)	387.43
Formula	C18H18FN5O2S
CAS No.	N/A
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 100 mg/mL
	Water: < 1mg/mL
	Ethanol:< 1mg/mL
Chemical Name	(3-((4-(4-fluoro-2-methoxyphenyl)-1, 3, 5-triazin-2-yl)amino)benzyl)(imino)(methyl)-l6-sulfanone
Synonyms	BAY1143572 S-Enantiomer; BAY 1143572 S-Enantiomer; BAY-1143572 S-Enantiomer

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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Delivery expected until 9/4/2025

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