« Back
Home /
dilmapimod-sb-681323

dilmapimod-sb-681323

Item no.	V3748-5mg
Manufacturer	InvivoChem LLC
CASRN	444606-18-2
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	444606-18-2
Available
Description	InvivoChem Cat #:V3748CAS #:444606-18-2 Purity >=98% Description: SB-681323 (also known as Dilmapimod; GW 681323) is a novel p38 MAPK inhibitor that has the potential to treat inflammatory diseases such as COPD (chronic obstructive pulmonary disease) and arthritis. SB-681323 inhibited the p38 MAPK pathway to a greater degree than prednisolone did. SB-681323 inhibited TNF-alpha production. SB-681323 is a potent p38 MAPK inhibitor that potentially suppresses inflammation in COPD. References: J Clin Pharmacol. 2010 Jan; 50(1):94-100. Related CAS#:937169-00-1 (tosylate)
Molecular Weight (MW)	456.42
Formula	C23H19F3N4O3
CAS No.	444606-18-2 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10 mM
	Water: N/A
	Ethanol: N/A
Chemical Name	8-(2, 6-difluorophenyl)-2-((1, 3-dihydroxypropan-2-yl)amino)-4-(4-fluoro-2-methylphenyl)pyrido[2, 3-d]pyrimidin-7(8H)-one
Synonyms	Dilmapimod; GW 681323; GW-681323; GW681323; SB681323; SB 681323; SB-681323

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 5mg

available

Delivery expected until 7/3/2025

Express Delivery: Save 17 days

Compare

Add to wishlist

Recommend by mail