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BMS-711939

BMS-711939

Item no.	V3800-5mg
Manufacturer	InvivoChem LLC
CASRN	1000998-62-8
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1000998-62-8
Available
Description	InvivoChem Cat #:V3800CAS #:1000998-62-8 Purity >=98% Description: BMS-711939, an analog of BMS-687453, is a novel potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC50 and IC50 of 4 nM for human PPARalpha and > 1000-fold selectivity vs human PPARgamma (EC50 of 4.5 uM) and PPARdelta (EC50 > 100 uM) in PPAR-GAL4 transactivation assays. BMS-711939 has an excellent pharmacological and safety profile in preclinical studies and thus was selected as a drug candidate for the treatment of atherosclerosis and dyslipidemia. BMS-711939 (10, 50, 100, p.o.) dose-dependently increases serum ApoA1 protein levels and low-density lipoprotein-cholesterol (LDLc) levels in mice. References: J Med Chem. 2010 Apr 8; 53(7):2854-64. Related CAS#:1000998-59-3 (BMS-687453)
Molecular Weight (MW)	462.86
Formula	C22H20ClFN2O6
CAS No.	1000998-62-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 30 mg/mL
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
Solubility (In vivo)	O=C(O)CN(CC1=CC(OCC2=C(C)OC(C3=CC=C(Cl)C=C3)=N2)=CC=C1F)C(OC)=O
Synonyms	BMS-711939; BMS 711939; BMS711939

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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