Comparison

Resminostat HCl

Item no. V3846-500mg
Manufacturer InvivoChem LLC
CASRN 1187075-34-8
Amount 500 mg
Quantity options 100 mg 10 mg 250 mg 25 mg 50 mg 5 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Available
Description
InvivoChem Cat #:V3846CAS #:1187075-34-8Purity >=98%

Description: Resminostat (formerly known as RAS-2410 and 4SC-201) is a potent inhibitor of HDAC (histone deacetylase) classes I and II (including HDAC1/3/6) with IC50 values ranging from 43 to 72 nmol/L. Resminostate has the potential to be used for the treatment of multiple myeloma (MM) due to its ability to induce histone H4 hyperacetylation, and apoptosis in MM cells. Recent study results have shown that, in MM cell lines, resminostat abrogates cell growth, suppresses proliferation and induce G0/G1 cell cycle arrest as well as interfering with Akt signaling pathway by decreasing phosphorylation of 4E-BP1 and p70S6k.

References: Br J Haematol. 2010 May; 149(4):518-28.

Related CAS#:864814-88-0 (free base)

Molecular Weight (MW)
385.86
Formula
C16H20ClN3O4S
CAS No.
1187075-34-8 (HCl);
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Solubility (In vitro)
DMSO: >= 50 mg/mL
Water: N/A
Ethanol: N/A
SMILES
O=C(NO)/C=C/C1=CN(S(=O)(C2=CC=C(CN(C)C)C=C2)=O)C=C1.[H]Cl
Synonyms
RAS2410 HCl; RAS-2410 HCl; RAS2410; RAS 2410; 4SC201; 4SC-201; 4SC 201 HCl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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