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azd7986

azd7986

Item no.	V3984-25mg
Manufacturer	InvivoChem LLC
CASRN	1802148-05-5
Amount	25mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V3984CAS #:1802148-05-5Purity >=98% Description: AZD7986 (formerly known as INS 1007) is a novel, second generation, highly potent, reversible, and selective DPP1 (Dipeptidyl peptidase 1) inhibitor pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively. It is free from aorta binding liabilities found for earlier compound series and has the potential for treating COPD (chronic obstructive pulmonary disease) with predicted human PK properties suitable for once daily human dosing. References: J Med Chem. 2016 Oct 27; 59(20):9457-9472.
Molecular Weight (MW)	420.47
Formula	C23H24N4O4
CAS No.	1802148-05-5
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: > 10 mM
	Water: N/A
	Ethanol: N/A
Chemical Name	(S)-N-((S)-1-cyano-2-(4-(3-methyl-2-oxo-2, 3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1, 4-oxazepane-2-carboxamide
Synonyms	INS 1007; INS-1007; INS1007; AZD7986; AZD-7986; AZD 7986

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 25mg

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