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Sapropterin dihydrochloride

Sapropterin dihydrochloride

Item no.	V4094-100mg
Manufacturer	InvivoChem LLC
CASRN	69056-38-8
Amount	100 mg
Quantity options	10 mg 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4094CAS #:69056-38-8Purity >=98% Description: Sapropterin dihydrochloride formerly known as Tetrahydrobiopterin (BH4, THB, trade name: Kuvan) or sapropterin is a synthetic preparation of the dihydrochloride salt of naturally occurring tetrahydrobiopterin (BH4) that is approved for the treatment of BH4 responsive PKU. It is a phenylalanine hydroxylase activator. Sapropterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative. Description: References: Mol Genet Metab. 2016 Jan; 117(1):5-11. References: Related CAS#:62989-33-7 (free base); 90366-07-7; 17528-72-2 (free base)
Molecular Weight (MW)	314.17
Formula	C9H17Cl2N5O3
CAS No.	69056-38-8 (HCl)
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: >= 60 mg/mL
	Water: N/A
	Ethanol: N/A
Chemical Name	(6R)-2-Amino-6-((1R, 2S)-1, 2-dihydroxypropyl)-5, 6, 7, 8-tetrahydro-4(1H)-pteridinone dihydrochloride
Synonyms	6R-BH4 dihydrochloride; 6R-Tetrahydro-L-biopterin dihydrochloride; Sapropterin HCl; BioMarin T 1401; Biopten; SN0588; SUN-0588; Tetrahydro-6-biopterin; Dapropterin; Phenoptin; THB; BPH4; 6R-BH4; Tetrahydrobiopterin, sapropterin; trade name Kuvan; Tetrahydrobiopterin Dihydrochloride, R-THBP Dihydrochloride
SMILES Code	O=C1N=C(N)NC2=C1N[CH]([CH](O)[CH](O)C)CN2.[H]Cl.[H]Cl

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Amount: 100 mg

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Delivery expected until 9/4/2025

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