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bay-677

bay-677

Item no.	V4164-100mg
Manufacturer	InvivoChem LLC
CASRN	2117404-84-7
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Available
Description	InvivoChem Cat #:V4164CAS #:2117404-84-7Purity >=98% Description: BAY-677 is an inactive and negative control for BAY-678. BAY-678 is a novel, potent, orally bioavailable, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). Description: References: ChemMedChem. 2015 Jul; 10(7):1163-73.; Bioorg Med Chem Lett. 2015 Oct 15; 25(20):4370-81. References: Related CAS#:675103-36-3 (BAY-678); 675103-35-2 (BAY-678 racemate)
	Name: BAY-677 CAS#: 2117404-84-7 (BAY-677); Chemical Formula: C20H15F3N4O2 Exact Mass: 400.1147 Molecular Weight: 400.36 Elemental Analysis: C, 60.00; H, 3.78; F, 14.24; N, 13.99; O, 7.99
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: BAY-677; BAY 677; BAY677 IUPAC/Chemical Name: 5-[(4S)-5-Acetyl-1, 2, 3, 4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile InChi Key: PGIVGIFOWOVINL-SFHVURJKSA-N InChi Code: InChI=1S/C20H15F3N4O2/c1-11-17(12(2)28)18(13-6-7-15(9-24)25-10-13)26-19(29)27(11)16-5-3-4-14(8-16)20(21, 22)23/h3-8, 10, 18H, 1-2H3, (H, 26, 29)/t18-/m0/s1 SMILES Code: N#CC1=NC=C([CH](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

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Amount: 100mg

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Delivery expected until 7/3/2025

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