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BALICATIB

BALICATIB

Item no.	V4361-5mg
Manufacturer	InvivoChem LLC
CASRN	354813-19-7
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	354813-19-7
Available
Description	InvivoChem Cat #:V4361CAS #:354813-19-7 Purity >=98% Description: Balicatib (also known as AAE-581) is a novel, potent and selective inhibitor of cathepsin K with 10-100 fold higher potency in cell-based enzyme occupancy assays than against cathepsin B, L, and S. As an inhibitor of the osteoclastic enzyme cathepsin K, Balicatib partially prevented ovariectomy-induced changes in bone mass, inhibited bone turnover at most sites, and had an unexpected stimulatory effect on periosteal bone formation. References: Osteoporos Int. 2011 Dec; 22(12):3001-11.
	Name: Balicatib CAS#: 354813-19-7 Chemical Formula: C23H33N5O2 Exact Mass: 411.26343 Molecular Weight: 411.54 Elemental Analysis: C, 67.12; H, 8.08; N, 17.02; O, 7.78
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: Balicatib; AAE581; AAE-581; AAE 581 IUPAC/Chemical Name: N-(1-((cyanomethyl)carbamoyl)cyclohexyl)-4-(4-propylpiperazin-1-yl)benzamide InChi Key: LLCRBOWRJOUJAE-UHFFFAOYSA-N InChi Code: InChI=1S/C23H33N5O2/c1-2-14-27-15-17-28(18-16-27)20-8-6-19(7-9-20)21(29)26-23(10-4-3-5-11-23)22(30)25-13-12-24/h6-9H, 2-5, 10-11, 13-18H2, 1H3, (H, 25, 30)(H, 26, 29) SMILES Code: O=C(NC1(C(NCC#N)=O)CCCCC1)C2=CC=C(N3CCN(CCC)CC3)C=C2

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Amount: 5 mg

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Delivery expected until 9/4/2025

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