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Resatorvid

Resatorvid

Item no.	V4598-10mg
Manufacturer	InvivoChem LLC
CASRN	243984-11-4
Amount	10 mg
Quantity options	100 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	243984-11-4
Available
Description	InvivoChem Cat #:V4598CAS #:243984-11-4Purity >=98% Description: Resatorvid (formerly also known as TAK-242) is a novel, cell-permeable and potent TLR4 (Toll-Like Receptor) signaling inhibitor which selectively inhibits the TLR4-mediated production of cytokines and nitric oxide. Resatorvid blocks LPS-induced production of NO, TNF-alpha, IL-6, and IL-1beta in macrophages with IC50 values of 1-11 nM. Resatorvid binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Resatorvid provides neuroprotection in experimental traumatic brain injury: implication in the treatment of human brain injury. References: Mol Pharmacol. 2006 Apr; 69(4):1288-95; Photochem Photobiol. 2016 Nov; 92(6):816-825.
	Name: Resatorvid CAS#: 243984-11-4 Chemical Formula: C15H17ClFNO4S Exact Mass: 361.0551 Molecular Weight: 361.8124 Elemental Analysis: C, 49.80; H, 4.74; Cl, 9.80; F, 5.25; N, 3.87; O, 17.69; S, 8.86
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: TAK-242; TAK 242; TAK242 IUPAC/Chemical Name: ethyl (R)-6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate InChi Key: LEEIJTHMHDMWLJ-CQSZACIVSA-N InChi Code: InChI=1S/C15H17ClFNO4S/c1-2-22-15(19)11-5-3-4-6-14(11)23(20, 21)18-13-8-7-10(17)9-12(13)16/h5, 7-9, 14, 18H, 2-4, 6H2, 1H3/t14-/m1/s1 SMILES Code: FC1=CC(Cl)=C(NS([CH]2CCCC=C2C(OCC)=O)(=O)=O)C=C1

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Amount: 10 mg

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Delivery expected until 10/2/2025

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