Comparison

CKI-7 2HCl

Item no. V5054-10mg
Manufacturer InvivoChem LLC
CASRN 1177141-67-1
Amount 10 mg
Quantity options 100 mg 250 mg 25 mg 50 mg
Category
Type Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias 1177141-67-1
Available
Description
InvivoChem Cat #:V5054CAS #:1177141-67-1 Purity >=98%

Description: CKI-7 2HCl is a novel, potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 uM and a Ki of 8.5 uM. CKI-7 also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 has a much weaker effect on casein kinase II and other protein kinases.

References: Acta Crystallogr D Biol Crystallogr. 2004 Oct; 60(Pt 10):1897-9.

Related CAS No.: 120615-25-0 (free base)

CKI-7 2HCl

Name: CKI-7 2HCl
CAS#: 1177141-67-1
Chemical Formula: C11H14Cl3N3O2S
Exact Mass: 356.9872
Molecular Weight: 358.66
Elemental Analysis: C, 36.84; H, 3.93; Cl, 29.65; N, 11.72; O, 8.92; S, 8.94
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: CKI-7 2HCl; CKI 7 2HCl; CKI7 2HCl; CKI-7 dihydrochloride; CKI 7 dihydrochloride; CKI7 dihydrochloride;
Chemical Name: N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
InChi Key: JUAVTXYOCISSSL-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16, 17)15-6-4-13)9-7-14-5-3-8(9)10; ; /h1-3, 5, 7, 15H, 4, 6, 13H2; 2*1H
SMILES Code: O=S(C1=CC=C(Cl)C2=C1C=NC=C2)(NCCN)=O.[H]Cl.[H]Cl

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 mg
Available: In stock
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