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lomustine-ccnu

lomustine-ccnu

Item no.	V5123-100mg
Manufacturer	InvivoChem LLC
CASRN	13010-47-4
Amount	100mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	13010-47-4
Available
Description	InvivoChem Cat #:V5123CAS #:13010-47-4Purity >=98% Description: Lomustine (also known as CCNU) is a nitrosourea anticancer drug that belongs to the class of DNA alkylating agents. Lomustine alkylates and crosslinks DNA, thereby inhibiting DNA and RNA synthesis. This agent also carbamoylates DNA and proteins, resulting in inhibition of DNA and RNA synthesis and disruption of RNA processing. Lomustine is lipophilic and thus able to cross the blood-brain barrier. References: J Neurosurg. 2015 Mar; 122(3):547-56.
	Name: Lomustine CAS#: 13010-47-4 Chemical Formula: C9H16ClN3O2 Exact Mass: 233.0931 Molecular Weight: 233.69524 Elemental Analysis: C, 46.26; H, 6.90; Cl, 15.17; N, 17.98; O, 13.69
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: NSC 79037; NSC-79037; NSC79037; Lomustinume. CeeNU; Belustin; Belustine; Cecenu; Citostal; Lomeblastin; Lucostin; Lucostine; Prava. CCNU.; RB1509; WR139017. Chemical Name: 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea InChi Key: GQYIWUVLTXOXAJ-UHFFFAOYSA-N InChi Code: InChI=1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H, 1-7H2, (H, 11, 14) SMILES Code: O=C(NC1CCCCC1)N(CCCl)N=O

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Amount: 100mg

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