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Setipiprant （ACT-129968; KYTH-105)

Setipiprant （ACT-129968; KYTH-105)

Item no.	V5219-5mg
Manufacturer	InvivoChem LLC
CASRN	866460-33-5
Amount	5 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	866460-33-5
Available
Description	InvivoChem Cat #:V5219CAS #:866460-33-5 Purity >=98% Description: Setipiprant (ACT-129968 and KYTH-105) is a novel, potent, orally bioavailable and selective CRTH2 antagonist. It has been shown to have greater specificity for DP2 (prostaglandin D2 receptor 2-CRTH2) than for DP1. CRTH2 is a G protein-coupled receptor for PGD2. Setipiprant at multiple oral doses was well tolerated and reduced both the allergen-induced LAR and the associated AHR in allergic asthmatics. CRTH2 may be a promising target for the treatment of allergic disorders. References: Allergy Asthma Clin Immunol. 2017; 13: 18.
	Name: Setipiprant CAS#: 866460-33-5 Chemical Formula: C24H19FN2O3 Exact Mass: 402.13797 Molecular Weight: 402.43 Elemental Analysis: C, 71.63; H, 4.76; F, 4.72; N, 6.96; O, 11.93
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: ACT-129968; ACT 129968; ACT129968; KYTH-105; KYTH105; KYTH 105 Chemical Name: 2-(2-(1-naphthoyl)-8-fluoro-1, 2, 3, 4-tetrahydro-5H-pyrido[4, 3-b]indol-5-yl)acetic acid InChi Key: IHAXLPDVOWLUOS-UHFFFAOYSA-N InChi Code: InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9, 12H, 10-11, 13-14H2, (H, 28, 29) SMILES Code: FC(C=C1)=CC2=C1N(CC(O)=O)C3=C2CN(C(C4=CC=CC5=CC=CC=C54)=O)CC3

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Amount: 5 mg

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Delivery expected until 12/4/2025

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