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glumetinib-scc244

glumetinib-scc244

Item no.	V5225-5mg
Manufacturer	InvivoChem LLC
CASRN	1642581-63-2
Amount	5mg
Category	Reagents & Chemicals Molecules
Type	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	1642581-63-2
Available
Description	InvivoChem Cat #:V5225CAS #:1642581-63-2Purity >=98% Description: Glumetinib (SCC244) is a novel, potent and highly selective c-Met kinase inhibitor with antitumor activity and with an IC50 of 0.42 nM. Glumetinib showed subnanomolar potency against c-Met kinase activity and high selectivity versus 312 other tested protein kinases, making it one of the most selective c-Met inhibitors described to date. Moreover, this inhibitor profoundly and specifically inhibits c-Met signal transduction and thereby suppresses the c-Met-dependent neoplastic phenotype of tumor and endothelial cells References: Mol Cancer Ther. 2018 Apr; 17(4):751-762.
	Name: Glumetinib CAS#: 1642581-63-2 Chemical Formula: C21H17N9O2S Exact Mass: 459.1226 Molecular Weight: 459.488 Elemental Analysis: C, 54.89; H, 3.73; N, 27.44; O, 6.96; S, 6.98
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Technical Information	Synonym: SCC244; SC-C244; SCC 244. Chemical Name: 6-(1-Methyl-1H-pyrazol-4-yl)-1-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1, 2-a]pyridin-3-yl]sulfonyl]-1H-pyrazolo[4, 3-b]pyridine InChi Key: RYBLECYFLJXEJX-UHFFFAOYSA-N InChi Code: InChI=1S/C21H17N9O2S/c1-27-11-16(7-24-27)14-3-4-20-23-10-21(29(20)13-14)33(31, 32)30-19-5-15(6-22-18(19)9-26-30)17-8-25-28(2)12-17/h3-13H, 1-2H3 SMILES Code: O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O

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Amount: 5mg

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Delivery expected until 7/3/2025

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