Human Total PDGF R alpha ELISA Kit Intracellular

Alpha-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRA gene.This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes

281-18000pg/ml

reactive with Human Total PDGF R alpha, reactivity with other related proteins not observed

Store at 2 - 8 C