« Back
Home /
Leptin Antagonist Quadruple Mutant Ovine Recombinant ( Leptin qA Ovine )

Leptin Antagonist Quadruple Mutant Ovine Recombinant ( Leptin qA Ovine )

Item no.	PT_41378_1mg
Manufacturer	Novateinbio
Amount	1 mg
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Peptides & Proteins Recombinant Proteins Obesity Endocrine Regulation of Lipid Metabolism
Type	Proteins Recombinant
Format	Lyophilized
Specific against	Sheep (Ovine, Ovis aries)
Purity	Greater than 98.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE.
Sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Arg.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Leptin Antagonist Quadruple Mutant Ovine Recombinant ( Leptin qA Ovine )
Similar products	Leptin Antagonist Quadruple Mutant Ovine Recombinant ( Leptin qA Ovine )
Available
Description	Leptin Antagonist Quadruple Mutant Ovine Recombinant is a single non-glycosilated polypeptide chain containing 146 amino and additional Ala at N-terminus acids and having a molecular mass of
Storage/Stability	Lyophilized Leptin-Antagonist Quadruple Mutant Ovine Recombinant although stable at room temperature for several weeks, should be stored desiccated below -18°C. Upon reconstitution at > 0.1 LEP-qA mutant mg/ml and up to 2mg/ml and filter sterilization Leptin mutant can be stored at 4°C or even room temperature for several weeks making it suitable for long term infusion studies using osmotic pumps. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is suggested. Please prevent freeze-thaw cycles.
Purity	Greater than 98.0% as determined by:(a) Gel filtration analysis.(b) Analysis by SDS-PAGE.
Form	The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.
Expression host	Escherichia coli.
Reagent Appearance	White lyophilized (freeze-dried) powder.
Amino acid sequence	The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Arg.
Biological Activity	ProSpecs leptin qA is capable of inhibiting leptin-induced proliferation of BAF/3 cells stably transfected with the long form of ovine leptin receptor. It also inhibits various leptin effects in several in vitro bioassays.
Solubility	It is recommended to reconstitute the lyophilized Leptin-Antagonist Quadruple Mutant Ovine Recombinant in sterile 0.4% NaHCO3 adjusted to pH 8-9, not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Manufacturers Category	Gastrointestinal Diseases

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 1 mg

available

Delivery expected until 9/11/2025

Express Delivery: Save 8 days

Compare

Add to wishlist

Get an offer