DOK4 cDNA

cDNA

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity). Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.

Human

608333

981bp

1. Centrifuge at 7000rpm for 1 minute.; ; 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.; ; Each tube contains approximately 10ug of lyophilized plasmid.

MATNFSDIVK QGYVKMKSRK LGIYRRCWLV FRKSSSKGPQ RLEKYPDEKS VCLRGCPKVTEISNVKCVTR LPKETKRQAV AIIFTDDSAR TFTCDSELEA EEWYKTLSVE CLGSRLNDISLGEPDLLAPG VQCEQTDRFN VFLLPCPNLD VYGECKLQIT HENIYLWDIH NPRVKLVSWPLCSLRRYGRD ATRFTFEAGR MCDAGEGLYT FQTQEGEQIY QRVHSATLAI AEQHKRVLLEMEKNVRLLNK GTEHYSYPCT PTTMLPRSAY WHHITGSQNI AEASSYAGEG YGAAQASSETDLLNRFILLK PKPSQGDSSE AKTPSQ

ATGGCGACCAATTTCAGTGACATCGTCAAGCAAGGCTACGTGAAGATGAAGAGCAGGAAGCTCGGGATCTACCGGAGGTGCTGGCTGGTGTTCCGGAAATCCTCCAGCAAGGGGCCCCAGCGGCTGGAGAAGTATCCAGATGAGAAGTCGGTGTGCCTCCGGGGCTGCCCCAAGGTGACTGAGATCAGCAACGTCAAGTGTGTTACGCGGCTCCCCAAGGAGACCAAGCGGCAGGCGGTGGCCATCATATTCACTGATGACTCGGCACGTACCTTCACCTGCGACTCAGAGCTAGAGGCAGAGGAGTGGTACAAGACACTATCTGTGGAGTGTCTGGGGTCCCGCCTCAACGACATCAGTCTGGGAGAACCTGACCTCCTGGCCCCAGGGGTGCAGTGTGAACAGACAGATCGCTTCAATGTCTTCCTGCTGCCCTGCCCCAACCTGGACGTGTATGGCGAGTGCAAGCTGCAGATCACCCACGAGAACATCTACCTCTGGGACATCCACAACCCCCGTGTGAAGCTCGTCTCGTGGCCCCTCTGCTCACTGCGCCGCTATGGCCGGGATGCCACACGCTTTACCTTCGAGGCTGGCCGGATGTGTGATGCTGGGGAAGGACTCTATACCTTCCAGACACAAGAGGGGGAGCAGATTTACCAGCGCGTCCACAGTGCCACCCTGGCCATCGCAGAGCAGCACAAGCGGGTCCTGCTGGAAATGGAGAAGAACGTGAGGCTGCTGAACAAGGGCACGGAACATTACTCGTATCCCTGCACACCCACGACCATGCTGCCGCGCAGTGCCTACTGGCACCACATCACTGGTTCCCAGAACATCGCCGAAGCCTCCAGCTATGCTGGTGAGGGGTATGGGGCAGCCCAGGCCAGCTCGGAAACAGACCTCCTCAACAGATTCATCCTGCTAAAGCCAAAGCCCAGCCAGGGGGACAGCAGTGAGGCCAAGACCCCATCCCAGTGA