IMPACT cDNA

cDNA

IMPACT belongs to the IMPACT family and contains 1 RWD domain. It is translational regulator that ensures constant high levels of translation under amino acid starvation and acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.

Human

615319

963bp

1. Centrifuge at 7000rpm for 1 minute.; ; 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.; ; Each tube contains approximately 10ug of lyophilized plasmid.

MAEGDAGSDQ RQNEEIEAMA AIYGEEWCVI DDCAKIFCIR ISDDIDDPKW TLCLQVMLPN EYPGTAPPIY QLNAPWLKGQ ERADLSNSLE EIYIQNIGES ILYLWVEKIR DVLIQKSQMT EPGPDVKKKT EEEDVECEDD LILACQPESS VKALDFDISE TRTEVEVEEL PPIDHGIPIT DRRSTFQAHL APVVCPKQVK MVLSKLYENK KIASATHNIY AYRIYCEDKQ TFLQDCEDDG ETAAGGRLLH LMEILNVKNV MVVVSRWYGG ILLGPDRFKH INNCARNILV EKNYTNSPEE SSKALGKNKK VRKDKKRNEH

ATGGCTGAGGGGGACGCAGGGAGCGACCAGAGGCAGAATGAGGAAATTGAAGCAATGGCAGCCATTTATGGCGAGGAGTGGTGTGTCATTGATGACTGTGCCAAAATATTTTGTATTAGAATTAGCGACGATATAGATGACCCCAAATGGACACTTTGCTTGCAGGTGATGCTGCCGAATGAATACCCAGGTACAGCTCCACCTATCTACCAGTTGAATGCTCCTTGGCTTAAAGGGCAAGAACGTGCGGATTTATCAAATAGCCTTGAGGAAATATATATTCAGAATATCGGTGAAAGTATTCTTTACCTGTGGGTGGAGAAAATAAGAGATGTTCTTATACAAAAATCTCAGATGACAGAACCAGGCCCAGATGTAAAGAAGAAAACTGAAGAGGAAGATGTTGAATGTGAAGATGATCTCATTTTAGCATGTCAGCCGGAAAGTTCGGTTAAAGCATTGGATTTTGATATCAGTGAAACTCGGACAGAAGTAGAAGTAGAAGAATTACCTCCGATTGATCATGGCATTCCTATTACAGACCGAAGAAGTACTTTTCAGGCACACTTGGCTCCAGTGGTTTGTCCCAAACAGGTGAAAATGGTTCTTTCCAAATTGTATGAGAATAAGAAAATAGCTAGTGCCACCCACAACATCTATGCCTACAGAATATATTGTGAGGATAAACAGACCTTCTTACAGGATTGTGAGGATGATGGGGAAACAGCAGCTGGTGGGCGTCTTCTTCATCTCATGGAGATTTTGAATGTGAAGAATGTCATGGTGGTAGTATCACGCTGGTATGGAGGGATTCTGCTAGGACCAGATCGCTTTAAACATATCAACAACTGTGCCAGAAACATACTAGTGGAAAAGAACTACACAAATTCACCTGAGGAGTCATCTAAGGCTTTGGGAAAGAACAAAAAAGTAAGAAAAGACAAGAAGAGGAATGAACATTAA