Mikrogen Diagnostik <i>recom</i>Line Helicobacter IgA 2.0 Lateral Strip Test Kit - 20 Tests

Next Day 2 - 8°C

The gram-negative, microaerophilic bacterium was described in 1983 by Warren and Marshall. It colonises the human stomach and is able to persist there in the long term. Approx. 50% of all humans worldwide are infected with Helicobacter pylori. While all those infected develop a chronic inflammation of the gastric mucosa, this leads to complaint symptoms only in a part of the patients. The Helicobacter pylori infection is believed to be linked to various gastric disorders, such as gastric ulcers, gastric adenocarcinomas and MALT lymphomas. As for its cause, host-related factors (social factors as well as nutritional and environmental factors) are, besides various virulent strains, also named as causal factors. The recomLine Helicobacter 2.0 detects antibodies against ten selected Helicobacter pylori antigens. The detection of antibodies against the two most important virulence factors, CagA and VacA, is of high diagnostic significance. These two virulence factors markedly increase the risk of premalignant changes, gastric carcinoma, MALT lymphoma and ulcer. The humoral immune response to the biomarkers GroEL, HtrA, NapA, HP231 and CtkA is associated with a severe course of disease. The recomLine Helicobacter 2.0 is the first serological test to present this selection of diagnostically relevant Helicobacter pylori markers.Research Use Only. For Sale In the United States Only. To purchase outside of the US, please contact Mikrogen.