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KAT1 (HAT1) Antibody (C-term) Blocking peptide

KAT1 (HAT1) Antibody (C-term) Blocking peptide

Item no.	ABC-BP1079b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	HAT1, KAT1, Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase 1
Available
Primary Accession	O14929
Bio Background	Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.
Bio References	Gronroos, E., et al., Mol. Cell 10(3):483-493 (2002).Makowski, A.M., et al., J. Biol. Chem. 276(47):43499-43502 (2001).Cheung, P., et al., Mol. Cell 5(6):905-915 (2000).Verreault, A., et al., Curr. Biol. 8(2):96-108 (1998).
Gene ID	8520
Gene Name	HAT1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1079b was selected from the C-term region of human HAT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 9/4/2025

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