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HDAC6 Antibody (N-term) Blocking Peptide

HDAC6 Antibody (N-term) Blocking Peptide

Item no.	ABC-BP1106b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	North, B.J., et al., Mol. Cell 11(2):437-444 (2003).Hubbert, C., et al., Nature 417(6887):455-458 (2002).Gao, L., et al., J. Biol. Chem. 277(28):25748-25755 (2002).Hook, S.S., et al., Proc. Natl. Acad. Sci. U.S.A. 99(21):13425-13430 (2002).Kirsh, O., et al., EMBO J. 21(11):2682-2691 (2002).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Histone deacetylase 6,HD6,HDAC6,KIAA0901
Similar products	HDAC6, KIAA0901, Histone deacetylase 6, HD6
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP1106b was selected from the N-term region of human HDAC6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	HDAC6 (histone deacetylase 6) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin, and has been shown to interact with HDAC11, SIRT2, and F-actin. HDAC6 is ubiquitinated, but its polyubiquitination however does not lead to degradation. HDAC is also a potential target of sumoylation.
Gene Name	HDAC6 {ECO:0000303\|PubMed:10220385, ECO:0000312\|HGNC:HGNC:14064}
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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