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NCOR1 Antibody (N-term) Blocking Peptide

NCOR1 Antibody (N-term) Blocking Peptide

Item no.	ABC-BP1121a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	NCOR1, KIAA1047, Nuclear receptor corepressor 1, N-CoR, N-CoR1
Available
Primary Accession	O75376
Bio Background	NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. The gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.
Bio References	Tai, H.H., et al., Biochem. Biophys. Res. Commun. 308(1):170-176 (2003).Ishizuka, T., et al., Mol. Cell. Biol. 23(15):5122-5131 (2003).Loinder, K., et al., J. Steroid Biochem. Mol. Biol. 84(1):15-21 (2003).Wang, S., et al., Oncogene 21(55):8388-8396 (2002).Baek, S.H., et al., Cell 110(1):55-67 (2002).
Gene ID	9611
Gene Name	NCOR1
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP1121a was selected from the N-term region of human NCOR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 11/6/2025

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