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PIAS1 Antibody (N-term) Blocking Peptide

PIAS1 Antibody (N-term) Blocking Peptide

Item no.	ABC-BP1242a
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Miyauchi, Y., et al., J. Biol. Chem. 277(51):50131-50136 (2002).Nishida, T., et al., J. Biol. Chem. 277(44):41311-41317 (2002).Tan, J.A., et al., J. Biol. Chem. 277(19):16993-17001 (2002).Megidish, T., et al., J. Biol. Chem. 277(10):8255-8259 (2002).Liu, B., et al., J. Biol. Chem. 276(39):36624-36631 (2001).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	E3 SUMO-protein ligase PIAS1,632-,DEAD/H box-binding protein 1,Gu-binding protein,GBP,Protein inhibitor of activated STAT protein 1,RNA helicase II-binding protein,PIAS1,DDXBP1
Similar products	PIAS1, DDXBP1, E3 SUMO-protein ligase PIAS1, DEAD/H box-binding protein 1, Gu-binding protein, Protein inhibitor of activated STAT protein 1, RNA helicase II-binding protein, GBP, 632-
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP1242a was selected from the N-term region of human PIAS1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PIAS1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in androgen receptor initiation and maintenance of spermatogenesis. The effects of transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
Gene Name	PIAS1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP1242a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 12/4/2025

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