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Bax Antibody (BH3 Domain Specific) Blocking peptide

Bax Antibody (BH3 Domain Specific) Blocking peptide

Item no.	ABC-BP1302a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Liu, F.T., et al., Biochem. Biophys. Res. Commun. 310(3):956-962 (2003).Roucou, X., et al., J. Biol. Chem. 278(42):40877-40881 (2003).Cao, X., et al., Blood 102(7):2605-2614 (2003).McJilton, M.A., et al., Oncogene 22(39):7958-7968 (2003).Bidere, N., et al., J. Biol. Chem. 278(33):31401-31411 (2003).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Apoptosis regulator BAX,Bcl-2-like protein 4,Bcl2-L-4,BAX,BCL2L4
Similar products	BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 56~76 of human Bax.
Bio Background	Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.
Gene Name	BAX
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 1/1/2026

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