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BAX Antibody (N-term) Blocking Peptide

BAX Antibody (N-term) Blocking Peptide

Item no.	ABC-BP13211a
Manufacturer	Abcepta
Amount	500 ug
Category	Oncology By Cell Type Carcinoma Hematology Lymphoma Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Montessuit, S., et al. Cell 142(6):889-901(2010)Ding, J., et al. J. Biol. Chem. 285(37):28749-28763(2010)Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :Yu, D.K., et al. Zhonghua Zhong Liu Za Zhi 32(5):324-327(2010)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Apoptosis regulator BAX,Bcl-2-like protein 4,Bcl2-L-4,BAX,BCL2L4
Similar products	BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP13211a was selected from the N-term region of BAX. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	The protein encoded by this gene belongs to the BCL2protein family. BCL2 family members form hetero- or homodimers andact as anti- or pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein forms aheterodimer with BCL2, and functions as an apoptotic activator.This protein is reported to interact with, and increase the openingof, the mitochondrial voltage-dependent anion channel (VDAC), whichleads to the loss in membrane potential and the release ofcytochrome c. The expression of this gene is regulated by the tumorsuppressor P53 and has been shown to be involved in P53-mediatedapoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
Gene Name	BAX
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-BP13211a-datasheet.pdf

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Amount: 500 ug

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Delivery expected until 1/1/2026

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