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CASP2 Antibody (Center) Blocking Peptide

CASP2 Antibody (Center) Blocking Peptide

Item no.	ABC-BP1327c
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Cell Biology Cell Status Apoptosis Peptides
Type	Peptides
Format	Lyophilized
Specific against	other
Citations	Lan,Q., Morton,L.M. Blood (2009) In pressShi,M., Vivian,C.J. Cell 136 (3), 508-520 (2009)Paroni,G., Henderson,C. J. Biol. Chem. 276 (24), 21907-21915 (2001)Tiso,N., Pallavicini,A. Biochem. Biophys. Res. Commun. 225 (3), 983-989 (1996)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Caspase-2,CASP-2,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD-2,Protease ICH-1,Caspase-2 subunit p18,Caspase-2 subunit p13,Caspase-2 subunit p12,CASP2,ICH1,NEDD2
Similar products	Caspase-2, CASP2, CASP-2, ICH1, NEDD2, NEDD-2, Neural precursor cell expressed developmentally down-regulated protein 2, Protease ICH-1, Caspase-2 subunit p12, Caspase-2 subunit p13, Caspase-2 subunit p18
Available
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP1327c was selected from the Center region of human CASP2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	CASP2 is a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. The protein exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli.
Gene Name	CASP2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 1/1/2026

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