PPP1CA Antibody (N-term) Blocking peptide

Peptides; Blocking Peptides

The protein encoded by this gene is one of the threecatalytic subunits of protein phosphatase 1 (PP1). PP1 is aserine/threonine specific protein phosphatase known to be involvedin the regulation of a variety of cellular processes, such as celldivision, glycogen metabolism, muscle contractility, proteinsynthesis, and HIV-1 viral transcription. Increased PP1 activityhas been observed in the end stage of heart failure. Studies inboth human and mice suggest that PP1 is an important regulator ofcardiac function. Mouse studies also suggest that PP1 functions asa suppressor of learning and memory. Three alternatively splicedtranscript variants encoding different isoforms have been found forthis gene.

Synthetic peptide