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TNF Antibody (C-term) Blocking peptide

TNF Antibody (C-term) Blocking peptide

Item no.	ABC-BP13532b
Manufacturer	Abcepta
Amount	500 ug
Category	Peptides & Proteins Peptides
Type	Peptides
Format	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	TNF-alpha, TNF, TNF-a, TNFA, soluble form, membrane form, TNFSF2, Tumor necrosis factor, Cachectin, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, Intracellular domain 1, Intracellular domain 2, C-domain 1, C-domain 2, NTF, ICD1, ICD2
Available
Primary Accession	P01375
Bio Background	This gene encodes a multifunctional proinflammatorycytokine that belongs to the tumor necrosis factor (TNF)superfamily. This cytokine is mainly secreted by macrophages. Itcan bind to, and thus functions through its receptorsTNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in theregulation of a wide spectrum of biological processes includingcell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety ofdiseases, including autoimmune diseases, insulin resistance, andcancer. Knockout studies in mice also suggested the neuroprotectivefunction of this cytokine.
Bio References	Majewski, P.M., et al. J. Biol. Chem. 285(45):34828-34838(2010)Kwon, H.J., et al. J. Immunol. 185(7):3980-3989(2010)Muller, T., et al. Scand. J. Immunol. 72(4):365-371(2010)Qin, H., et al. J. Int. Med. Res. 38(3):760-768(2010)Acharyya, S., et al. PLoS ONE 5 (8), E12479 (2010) :
Gene ID	7124
Gene Name	TNF
Subtitle	Synthetic peptide
Target/Specificity	The synthetic peptide sequence used to generate the antibody AP13532b was selected from the C-term region of TNF. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

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Delivery expected until 10/2/2025

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