Comparison

FAP Antibody (Center) Blocking peptide

Item no. ABC-BP13766c
Manufacturer Abcepta
Amount 500 ug
Category
Type Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products soluble form, Seprase, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, SIMP, Prolyl endopeptidase FAP, Dipeptidyl peptidase FAP, FAPalpha, Serine integral membrane protease, Surface-expressed protease, APCE, 3421-, Antiplasmin-cleaving enzyme FAP, FAP (HGNC:3590)
Available
Primary Accession
Q12884
Bio Background
The protein encoded by this gene is a homodimeric integralmembrane gelatinase belonging to the serine protease family. It isselectively expressed in reactive stromal fibroblasts of epithelialcancers, granulation tissue of healing wounds, and malignant cellsof bone and soft tissue sarcomas. This protein is thought to beinvolved in the control of fibroblast growth orepithelial-mesenchymal interactions during development, tissuerepair, and epithelial carcinogenesis.
Bio References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ospelt, C., et al. Arthritis Rheum. 62(5):1224-1235(2010)Stremenova, J., et al. Int. J. Oncol. 36(2):351-358(2010)Chen, H., et al. Exp. Mol. Pathol. 87(3):189-194(2009)Dohi, O., et al. Histopathology 55(4):432-440(2009)
Gene ID
2191
Gene Name
FAP (HGNC:3590)
Subtitle
Synthetic peptide
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP13766c was selected from the Center region of FAP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 ug
Available: In stock
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