CIDEA Antibody (C-term) Blocking peptide

Peptides; Blocking Peptides

This gene encodes the homolog of the mouse protein Cideathat has been shown to activate apoptosis. This activation ofapoptosis is inhibited by the DNA fragmentation factor DFF45 butnot by caspase inhibitors. Mice that lack functional Cidea havehigher metabolic rates, higher lipolysis in brown adipose tissueand higher core body temperatures when subjected to cold. Thesemice are also resistant to diet-induced obesity and diabetes. Thissuggests that in mice this gene product plays a role inthermogenesis and lipolysis. Alternatively spliced transcripts havebeen identified.

Synthetic peptide