MYC Antibody (C-term T400) Blocking Peptide

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as atranscription factor that regulates transcription of specifictarget genes. Mutations, overexpression, rearrangement andtranslocation of this gene have been associated with a variety ofhematopoietic tumors, leukemias and lymphomas, including Burkittlymphoma. There is evidence to show that alternative translationinitiations from an upstream, in-frame non-AUG (CUG) and adownstream AUG start site result in the production of two isoformswith distinct N-termini. The synthesis of non-AUG initiated proteinis suppressed in Burkitt's lymphomas, suggesting its importance inthe normal function of this gene.

4609

Synthetic peptide